UVA Clinical Data Repository (CDR)
The UVA Clinical Data Repository (CDR) is a HIPAA-compliant integrated research database containing deidentified clinical and administrative information on over 1 million patients and five million clinical encounters at UVA. Additional detail is available with IRB permission. UVA researchers may apply for CDR accounts, which provide access to a private online workspace that allows execution of searches to create patient populations. Populations may then be explored and compared using a variety of standard reports, targeted searches, code and ontology navigators, and "drill down" to data values.
Accounts, CDR user training, and user support are available from Jason Lyman or Ken Scully in the Division of Biomedical Informatics of the Department of Public Health Sciences. Users with accounts can access the CDR here.
MuSIC Research Databases
The Multi-Schema Information Capture (MuSIC) framework was created at UVA to allow rapid and flexible development of Web-based custom research databases for a variety of purposes. Research databases with a generic Web user interface can be developed rapidly within the MuSIC framework and then customized to yield an optimal online display. Data is maintained by UVA ITS in a protected environment with automated backup, and automatically-updating data sets can be shared from the UVA Clinical Data Repository into the MuSIC environment. MuSIC is appropriate for research registries, studies that integrate clinical and other data such as surveys, and simple clinical studies that do not require a full-scale clinical trials management system. MuSIC may be accessed by collaborating researchers outside of UVA, including international sites, and the framework may be included in grant applications as a foundation for project data management.
The Cancer Biomedical Informatics Group administers OnCore, a commercial Web application that coordinates the data collection and staff workflow across all UVA oncology clinical research teams.
The Group has developed interfaces that link other systems to OnCore. IRB review information and informed consent versions are linked with the UVA HSR-IRB and with NIH's Central IRB (CIRB).